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IHC

Immunohistochemistry (IHC) combines immunological and enzymatic techniques to localize and evaluate antigen expression in tissue sections. Single-stain immunohistochemistry may be evaluated by pathologist light microscopic review or image analysis. Mosaic’s IHC assays are focused on immuno-oncology, immunology, signal-transduction pathways and relevant targets for cancer therapy. Mosaic has experience testing over a thousand antibodies for IHC and is validating numerous new assays on a rolling basis. Please contact us if the assay of interest is not on our list.

Single Analyte IHC – Marker List
15PGDH
20S Proteasome Subunit Alpha 5
4E-BP1
5T4
Androgen Receptor (AR)
AKT
ALPP (PLAP)
ALPPL2
Angiopoietin 1
Angiopoietin 2
ASGPR1
Aurora A
Aurora B
Aurora C
AXL
B7-H3
BAX
BCL-2
BCL-6
BCL-xL
BCMA
Beta-Catenin
BIM
BMI1
BRAF
BRG1
c-KIT (CD117)
c-MET
c-MYC
CAIX
CCR2
CCR6
CCR8
CD3
CD4
CD8
CD10
CD11b
CD11c
CD15
CD16
CD19
CD20
CD27
CD27 Ligand
CD28
CD30
CD31
CD33
CD34
CD37
CD38
CD40
CD40 Ligand
CD45R0
CD45 LCA
CD55
CD56 (Neural Cell Adhesion Molecule)
CD57
CD68
CD72
CD73
CD73 Enzymatic Assay
CD80
CD83
CD86
CD110
CD133
CD134 (OX40)
CD137
CD138
CD141
CD163
CD200
CEA
CEACAM5
CEACAM6
CH24H (CYP46)
CHK1
Chromogranin A
cIAP1
Cleaved Caspase 3
CLDN2 (Claudin 2)
CLDN18 (Claudin-18)
CLEC9A
COX2
CTLA-4
CXCR3
CXCR4
Cyclin D1 (Bcl-1)
Cyclin E1
Cytokeratin AE1/AE3
Cytokeratin, LMW, CAM5.2
DDR1
DDR2
DHODH
DNAM (CD226)
DNMT1
DR5 (TRAIL-R2)
E-Cadherin
EGFR
Endocan
ER (Estrogen Receptor)
ERCC1
ERCC5
ERK
ERK1
ERK2
FAK
FASN
FGL1
FGFR4
Fibroblast Activation Protein, Alpha (FAP)
FoxM1
Foxp3
Fucosyl-GM1
GALNT14
GITR
GFAP
GLI-2
Glypican-3
GPNMB
Granzyme B
GSK3 beta
HB-EGF
hENT1
HER2 (HercepTest)
HER3
HER4
Heregulin
HGF
HIF-1 alpha
HSP47
HSP70
ICOS
IDO
IGF1R Beta
IL8
Integrin Beta 3
Integrin Beta 6
Kappa Light Chain
Ki-67
LAG3
LDLR
MAGE-A
MCL-1
MDM2
MDR-1 (P-glycoprotein)
Mesothelin
MHCI (HLA Class I ABC)
MHCII (HLA Class II DP, DQ, DR Antigen)
MLH1
MSH2
MSH6
MTAP
MUC1
MUC13
MUC16
MUM1
Murine B7H3
Murine CD4
Murine CD8a
Murine CD25
Murine CD31 (PECAM)
Murine CD38
Murine CD68
Murine F4/80 (Macrophage Marker)
Murine FoxP3
Myeloperoxidase (MPO)
Nectin-2
NF2
NKp46 (NCR1)
NRLP3
NRP-1 (Neuropilin-1)
Nucleophosmin
NYESO-1
OX40L (CD252)
p16
p21 (Waf1/Cip1)
p27
p53
p70 S6 Kinase
p-Cadherin
PAR2
PAX-5
PCNA
PD-1
PD-L1 (Clone 22C3)
PD-L1 (Clone 28-8)
PD-L1 (Clone 73-10)
PD-L1 (Clone E1L3N)
PD-L1 (Clone SP142)
PD-L1 (Clone SP263)
PD-L2
PDGFR-beta
Perforin
Phospho-4E-BP1 (Thr37/46)
Phospho-ACC (Ser79)
Phospho-AKT (Ser473)
Phospho-AKT (Thr308)
Phospho-Aurora A (Thr288)
Phospho-BAD (Ser136)
Phospho-CAD (Ser1859)
Phospho-EGFR (Tyr1068)
Phospho-EGFR (Tyr1086)
Phospho-EGFR (Tyr1173)
Phospho-ERK1/2
Phospho-FAK (Tyr397)
Phospho-FLT3 (Tyr591)
Phospho-FRS2 (Tyr436)
Phospho-GSK3B (Ser9/21)
Phospho-Gamma H2AX
Phospho-HER2 (Tyr1221/1222)
Phospho-HER3 (Tyr1289)
Phospho-Histone H3 (Ser10)
Phospho-Histone H3 (Ser28) (pHH3)
Phospho-IGF1R (Tyr 1161)
Phospho-JNK (Thr183/Tyr185)
Phospho-JUN (Ser73)
Phospho-KAP1 (Ser824)
Phospho-MEK (Ser217/221)
Phospho-MET (Tyr1003)
Phospho-MET (Tyr1230/1234/1235)
Phospho-MET (Tyr1349)
Phospho-NDRG1 (Thr346)
Phospho-p21 (Thr145)
Phospho-p53 (Ser33)
Phospho-p68 (Tyr593)
Phospho-p70 S6 Kinase (Thr389)
Phospho-p90RSK (Ser380)
Phospho-PRAS40 (Thr246)
Phospho-RB (Ser807/811)
Phospho-RET (Tyr1062)
Phospho-S6 Ribosomal Protein (Ser235/236)
Phospho-S6 Ribosomal Protein (Ser240/244)
Phospho-SRC (Tyr416)
Phospho-STAT3 (Tyr705)
Phospho-STAT5 (Tyr694)
Phospho-Vimentin (Ser82)
Phospho-YB1 (Ser102)
PI3K p110alpha
PI3K p110beta
PI3K p110delta
PI3K p110gamma
PIM-1
PIM-2
PIM-3
PLK1
PLXB2
PMS2
Podoplanin
PPAR gamma
PR (Progesterone Receptor)
PRAS40
PSMA (Prostate Specific Membrane Antigen)
PTEN
PVR (Poliovirus Receptor)
Rat CD8
ROR1
RXR alpha
S100
S6 Ribosomal Protein
SDMA
SHH
SMA (Smooth Muscle Actin)
SRC
STAT3
STING
Survivin
Synaptophysin
TACI
TCF7
TDO2
TGF Beta
TIE-2
TIGIT
TIM1
TIM3
TIP47 (Perilipin 3)
TLR-7
Tri-Methyl-Histone H3 (Lys27) [H3K27me3]
TUNEL Assay
VEGFA
VEGFR2
WT1
XIAP
YB1