Mosaic Laboratories offers mutation testing for the following genes:
Please enquire if you are interested in a gene not on the list.
Test Name: HIF1-alpha
Alternative Name(s): Hypoxia Inducible Factor 1 Subunit Alpha, Class E Basic Helix-Loop-Helix Protein 78, MOP1
Test Description: Hypoxia inducible factor 1 subunit alpha (HIF1-alpha) is a nuclear protein that plays a critical role in mammalian cell response to oxygen deprivation.
Test Name: 15PGDH
Alternative Name(s): 15-hydroxyprostaglandin dehydrogenase
Test Description: 15-hydroxyprostaglandin dehydrogenase (15-PGDH) catalyzes NAD+-linked oxidation of 15 (S)-hydroxyl group of prostaglandins and lipoxins. 15-PGDH is a gene that is often down-regulated in cancer.
Test Name: Nectin-2
Alternative Name(s): Nectin Cell Adhesion Molecule 2, PVRL2, CD112, Nectin-2L2, HVEB
Test Description: Nectin-2 is a single-pass type I membrane glycoprotein which serves as a major plasma membrane component of adherens junctions.
Test Name: Phospho-ACC (Ser79)
Alternative Name(s): BMS1
Test Description: B-cell specific moloney leukemia virus insertion-site 1 (pACC) is a member of the polycomb group (PcG) proteins, which has been shown to play a critical role in cancer development and recurrence. pACC controls the cell cycle and promotes cell proliferation by suppressing tumor pathways such as p16INK4a, MDM2, and p53.